Reply to DB Shennan

The Authors’ Reply

The Authors’ Reply

Shennan-type evolution of stone-age cultural innovation

The computer simulations of Shennan (2001) are complemented by assuming the environment to change randomly. For moderate change rates, fitness optimisation through evolution is still possible. Shennan (2001), based on a biological model of Peck et al (1997), showed that in large populations, evolution in a computer model can evolve to a higher average fitness than in a smaller population. This ...

Reply to the Letter to the Editor Reply to

We thank Dr Schachner for his interest and comments on our recent experimental findings [1]. The first facet of our study was that although initially (at 1 month), neointima formation in vein grafts was inhibited by perivenous application of fibrin glue at the time of implantation, at 4 months neointimal formation was not significantly different from controls [1]. Dr Schachner has implied that ...

Reply to the Letter to the Editor Reply to VonOppell

We appreciate the comments of Drs von Oppell and Rammohan on our article. The definition in our paper relates specifically to deep sternal wound infections and we appreciate that perhaps this is not made abundantly clear in the methodology. Superficial wound infections were defined as those that do not penetrate the subcutaneous tissue layer. The wound may exhibit erythema and a small amount of...